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TAGMe DNA Methylation Detection Kits (qPCR) rau Endometrial Cancer Launches Era of Endometrial Cancer Diagnosis and Treatment 2.0

Kev daws rau mob qog noj ntshav endometrial, tshem tawm cov qog nqaij hlav ntawm theem ntawm cov kab mob precancerous.Kev mob qog noj ntshav endometrial yog ib qho ntawm peb qhov mob qog noj ntshav loj hauv gynecology.

Kev mob qog noj ntshav endometrial yog ib qho mob qog noj ntshav ntau tshaj plaws hauv cov poj niam cev xeeb tub, nyob rau qib thib ob ntawm cov poj niam cev xeeb tub malignancies hauv Suav teb, thiab muaj ntau dua hauv cov poj niam hauv nroog.Raws li kev txheeb cais los ntawm Lub Chaw Haujlwm Saib Xyuas Kev Tshawb Fawb Thoob Ntiaj Teb rau Kev Kho Mob ntawm Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv, muaj kwv yees li 420,000 tus neeg mob tshiab ntawm endometrial cancer thoob ntiaj teb xyoo 2020, muaj txog 100,000 tus neeg tuag.

Ntawm cov xwm txheej no, kwv yees li 82,000 tus neeg mob tshiab ntawm endometrial cancer tau tshaj tawm hauv Suav teb, muaj txog 16,000 tus neeg tuag.Nws kwv yees tias los ntawm 2035, yuav muaj 93,000 tus neeg mob tshiab ntawm endometrial cancer hauv Suav teb.

Kev kho mob rau cov qog nqaij hlav endometrial thaum ntxov yog qhov siab heev, nrog rau 5-xyoo txoj sia nyob txog li 95%.Txawm li cas los xij, 5-xyoo txoj sia nyob rau theem IV endometrial cancer tsuas yog 19%.

Kev mob qog noj ntshav endometrial feem ntau tshwm sim hauv cov poj niam postmenopausal thiab perimenopausal, nrog qhov pib muaj hnub nyoog nruab nrab ntawm 55 xyoo.Txawm li cas los xij, nyob rau xyoo tas los no, tau muaj kev nce ntxiv hauv kev mob qog noj ntshav endometrial ntawm cov poj niam hnub nyoog 40 thiab qis dua.

Tam sim no tsis muaj txoj hauv kev tshuaj xyuas tsim nyog rau kev mob qog noj ntshav endometrial

Rau cov poj niam uas muaj hnub nyoog yug me nyuam, kev tshuaj xyuas ntxov thiab kev tswj xyuas raws sij hawm ntawm kev mob qog noj ntshav endometrial tuaj yeem ua rau kom muaj txiaj ntsig zoo tshaj plaws thiab muab txoj hauv kev rau kev muaj sia nyob mus ntev.

Txawm li cas los xij, tam sim no tsis muaj rhiab heev thiab muaj tseeb uas tsis yog kev tshuaj ntsuam xyuas rau kev mob qog noj ntshav endometrial hauv kev kho mob.Cov tsos mob xws li los ntshav los ntawm qhov chaw mos thiab qhov chaw mos thaum ntxov tau yooj yim saib xyuas, ua rau tsis muaj sijhawm rau kev kuaj mob ntxov.

Kev tshuaj xyuas ua ntej siv ultrasound imaging thiab kev kuaj gynecological niaj hnub muaj qhov rhiab heev.

Kev siv hysteroscopy thiab pathological biopsy yog invasive, nrog rau cov tshuaj loog siab thiab nqi, thiab tej zaum yuav ua rau los ntshav, kab mob, thiab uterine perforation, ua rau ib tug siab tus nqi ntawm tsis tau kuaj mob, thiab tsis yog siv raws li ib tug niaj hnub tshuaj ntsuam txoj kev.

Endometrial biopsy sampling tej zaum yuav ua rau tsis xis nyob, los ntshav, kis kab mob, thiab uterine perforation, ua rau muaj tus nqi siab ntawm kev kuaj tsis tau.

TAGMe DNA Methylation Detection Kits (qPCR) rau Endometrial CancerLaunches Era of Endometrial Cancer Diagnosis and Treatment 2.0

TAGMe DNA Methylation Detection Kits (qPCR) rau Endometrial Cancertuaj yeem ua tau zoo ntxiv rau qhov tsis txaus ntawm cov qauv kev tshuaj ntsuam xyuas rau kev mob qog noj ntshav endometrial, txo qhov kev kuaj mob tsis tau zoo thiab pab cov neeg mob txhawm rau kuaj mob qog noj ntshav raws sijhawm.

Kev kuaj ob qhov muag tsis pom kev yog "tus qauv kub" rau kev siv tau zoo thiab tseem yog tus qauv kho mob uas Epiprobe ib txwm ua raws li!

Cov txiaj ntsig ntawm kev sim ob qhov muag tsis pom kev pom tau tias rau cov qauv kuaj lub ncauj tsev menyuam, AUC yog 0.86, qhov tshwj xeeb yog 82.81%, thiab rhiab heev yog 80.65%;Rau cov qauv ntawm lub tsev menyuam txhuam hniav, AUC yog 0.83, qhov tshwj xeeb yog 95.31%, thiab rhiab heev yog 61.29%.

Rau cov khoom kuaj mob qog noj ntshav thaum ntxov, lub hom phiaj tseem ceeb yog txhawm rau tshuaj xyuas cov tib neeg uas muaj teeb meem ntau dua li kev kuaj pom tseeb.

Rau cov khoom kuaj mob qog noj ntshav thaum ntxov, txiav txim siab tias lub hom phiaj ntawm cov neeg siv kev siv yog txhawm rau tshem tawm qhov kev pheej hmoo ntawm kev mob nkeeg thiab kom tsis txhob muaj kev kuaj mob ploj mus ntau li ntau tau yog lub siab dawb siab tshaj rau cov neeg kuaj.

Qhov tsis zoo kwv yees tus nqi ntawmTAGMe DNA Methylation Detection Kits (qPCR) rau Endometrial Canceryog 99.4%, uas txhais tau hais tias nyob rau hauv cov pej xeem ntawm cov neeg uas tau txais txiaj ntsig tsis zoo, 99.4% ntawm cov txiaj ntsig tsis zoo yog qhov tseeb tsis zoo.Lub peev xwm los tiv thaiv kev kuaj mob tsis pom zoo yog qhov zoo heev, thiab feem ntau ntawm cov neeg siv tsis zoo tuaj yeem tau txais kev pom zoo tias lawv tsis tas yuav tsum tau kuaj xyuas qhov tsis txaus ntseeg nrog cov kev kuaj mob siab.Qhov no yog qhov kev tiv thaiv zoo tshaj plaws rau cov neeg siv.

Kev ntsuam xyuas tus kheej ntawm cov xwm txheej txaus ntshai rau mob qog noj ntshav endometrial.

Nrog rau kev txhim kho ntawm kev ua neej nyob, qhov tshwm sim ntawm cov qog nqaij hlav endometrial hauv Suav teb tau nce zuj zus txhua xyoo, thiab muaj kev sib txawv rau cov neeg mob hluas.

Yog li, hom neeg twg muaj feem yuav mob qog noj ntshav endometrial?

Feem ntau hais lus, cov neeg uas muaj feem yuav mob qog noj ntshav endometrial muaj rau 6 yam hauv qab no:

  1. Muaj kev txom nyem los ntawm cov kab mob metabolic: ib tus kab mob uas tshwm sim los ntawm kev rog, tshwj xeeb tshaj yog mob plab, nrog rau cov ntshav qab zib siab, cov ntshav lipids txawv txav, ntshav siab, thiab lwm yam, uas cuam tshuam rau kev noj qab haus huv ntawm lub cev;
  2. Lub sij hawm ntev ib leeg estrogen stimulation: mus ntev raug rau ib leeg estrogen stimulation yam tsis sib xws progesterone los tiv thaiv endometrium;
  3. Thaum ntxov menarche thiab lig menopause: qhov no txhais tau hais tias tus naj npawb ntawm kev coj khaub ncaws ntau zuj zus, yog li lub endometrium raug rau estrogen stimulation rau lub sij hawm ntev;
  4. Tsis pub yug menyuam: thaum cev xeeb tub, qib ntawm progesterone hauv lub cev yog siab, uas tuaj yeem tiv thaiv endometrium;
  5. Cov yam ntxwv ntawm caj ces: qhov classic tshaj plaws yog Lynch syndrome.Yog tias muaj cov menyuam yaus ntawm mob qog noj ntshav, mob plab, lossis poj niam cov txheeb ze uas muaj qog noj ntshav ntawm zes qe menyuam, mob qog noj ntshav endometrial, thiab lwm yam ntawm cov neeg txheeb ze, nws yuav tsum tau sau tseg thiab kev sib tham txog caj ces thiab kev ntsuam xyuas tuaj yeem ua tau;
  6. Kev ua neej tsis zoo: xws li haus luam yeeb, tsis muaj kev tawm dag zog, thiab nyiam cov khoom noj uas muaj calorie ntau thiab muaj rog xws li qos yaj ywm chips, french fries, mis nyuj tshuaj yej, zaub mov kib, ncuav qab zib chocolate, thiab lwm yam, yog li nws yuav tsum tau ua kom muaj kev tawm dag zog. ntau tom qab noj lawv.

Koj tuaj yeem sib piv koj tus kheej nrog 6 tus yam ntxwv saum toj no uas muaj feem yuav mob qog noj ntshav endometrial, thiab sim kho lawv kom ntau li ntau tau los tiv thaiv nws los ntawm qhov chaw.

 


Post lub sij hawm: May-09-2023