TAGMe DNA Methylation Detection Kits (qPCR) rau Endometrial Cancer
KHOOM NTA
Precision
Validated ntau tshaj 800 kuaj kuaj nyob rau hauv ob-dig muag multi-center kev tshawb fawb, cov khoom muaj ib tug meej ntawm 82.81% thiab rhiab heev ntawm 80.65%.
Yooj yim
Thawj Me-qPCR methylation nrhiav tshuab tuaj yeem ua tiav hauv ib kauj ruam hauv 3 teev yam tsis muaj kev hloov pauv bisulfite.
Thaum ntxov
Detectable nyob rau theem precancerous.
Automation
Muaj feem xyuam nrog lub ncauj tsev menyuam txhuam thiab Pap smear kuaj.
YUAV TSUM SIV
Cov khoom siv no yog siv rau hauv vitro qualitative nrhiav pom ntawm hypermethylation ntawm cov noob PCDHGB7 incervical specimens.Cov txiaj ntsig zoo qhia tau tias muaj kev pheej hmoo ntau ntxiv ntawm cov kab mob endometrial precancerous thiab mob qog noj ntshav, uas yuav tsum tau kuaj xyuas histopathological ntxiv ntawm endometrium.Ntawm qhov tsis sib xws, cov txiaj ntsig tsis zoo qhia tau hais tias qhov kev pheej hmoo ntawm endometrial precancerous lesions thiab mob qog noj ntshav yog tsawg, tab sis qhov kev pheej hmoo tsis tuaj yeem suav nrog tag nrho.Kev kuaj mob zaum kawg yuav tsum yog raws li kev soj ntsuam histopathological ntawm endometrium.PCDHGB7 yog ib tug tswv cuab ntawm tsev neeg protocadherin γ gene pawg.Protocadherin tau pom los tswj cov txheej txheem lom neeg xws li cell proliferation, cell cycle, apoptosis, ntxeem tau, tsiv teb tsaws thiab autophagy ntawm cov qog hlwb los ntawm ntau txoj kev taw qhia, thiab nws cov noob ntsiag to tshwm sim los ntawm hypermethylation ntawm thaj chaw txhawb nqa yog ze ze rau qhov tshwm sim thiab kev loj hlob. ntawm ntau yam mob qog noj ntshav.Nws tau raug tshaj tawm tias hypermethylation ntawm PCDHGB7 yog txuam nrog ntau hom qog nqaij hlav, xws li non-Hodgkin lymphoma, mob qog noj ntshav mis, mob qog noj ntshav, mob qog noj ntshav, thiab qog nqaij hlav qog.
DETECTION PRINCIPLE
Cov khoom siv no muaj cov nucleic acid extraction reagent thiab PCR nrhiav reagent.Nucleic acid yog muab rho tawm los ntawm magnetic-bead-based method.Cov khoom siv no yog ua raws li lub hauv paus ntsiab lus ntawm fluorescence quantitative PCR txoj kev, siv cov tshuaj methylation-specific real-time PCR cov tshuaj tiv thaiv los soj ntsuam cov qauv DNA, thiab ib txhij tshawb xyuas CpG qhov chaw ntawm PCDHGB7 noob thiab cov cim kev tswj kom zoo hauv kev siv cov noob tawg G1 thiab G2.Cov qib methylation ntawm PCDHGB7 hauv cov qauv, lossis Me tus nqi, yog xam raws li PCDHGB7 gene methylated DNA amplification Ct tus nqi thiab Ct tus nqi ntawm kev siv.PCDHGB7 gene hypermethylation zoo lossis tsis zoo yog txiav txim siab raws li Me tus nqi.
Daim ntawv thov scenarios
Kev tshuaj ntsuam thaum ntxov
Cov neeg noj qab haus huv
Kev soj ntsuam kev pheej hmoo mob qog noj ntshav
Cov pab pawg muaj kev pheej hmoo siab (cov neeg uas muaj qhov txawv txav ntawm qhov chaw mos los ntshav tom qab lub cev tsis muaj zog, endometrial thickening, thiab lwm yam)
Kev soj ntsuam rov tshwm sim
Prognostic pejxeem
Clinical tseem ceeb
Kev tshuaj xyuas ntxov rau cov neeg noj qab haus huv:Cov qog nqaij hlav endometrial thiab cov kab mob precancerous tuaj yeem kuaj pom tseeb;
Kev ntsuas kev pheej hmoo rau cov neeg muaj kev pheej hmoo siab:Kev soj ntsuam kev pheej hmoo tuaj yeem ua rau cov neeg muaj qhov txawv txav ntawm qhov chaw mos los ntshav thiab endometrial thickening tom qab menopause los pab rau kev kuaj mob;
Prognostic population recurrence monitoring:Kev tshuaj xyuas cov neeg rov qab ua dua tuaj yeem ua tau los tiv thaiv kev qeeb hauv kev kho mob los ntawm kev rov ua dua.
Qauv sau
Txoj kev coj mus kuaj: Muab cov khoom pov tseg ntawm ncauj tsev menyuam rau ntawm lub ncauj tsev menyuam, maj mam rub lub ncauj tsev menyuam txhuam thiab tig 4-5 zaug clockwise, maj mam tshem lub ncauj tsev menyuam txhuam, muab tso rau hauv lub cell preservation tov, thiab sau npe rau kev kuaj hauv qab no.
Kev khaws cia ntawm cov qauv:Cov qauv tuaj yeem khaws cia hauv chav sov txog li 14 hnub, ntawm 2-8 ℃ txog li 2 lub hlis, thiab ntawm -20 ± 5 ℃ txog li 24 lub hlis.
Cov txheej txheem tshawb pom: 3 Teev (Tsis muaj phau ntawv txheej txheem)
TAGMe DNA Methylation Detection Kits (qPCR) rau Endometrial Cancer
| Daim ntawv thov kev kho mob | Clinical auxiliary diagnosis ntawm endometrial carcinoma |
| Kev kuaj gene | PCDHGB 7 |
| Hom qauv | Poj niam cev xeeb tub |
| Kev sim | Fluorescence quantitative PCR technology |
| Cov qauv siv tau | AB 7500 |
| Packing specification | 48 xeem/kit |
| Kev cia khoom | Cov khoom siv A yuav tsum khaws cia ntawm 2-30 ℃ Cov khoom siv B yuav tsum khaws cia ntawm -20 ± 5 ℃ Siv tau mus txog 12 lub hlis. |
Txog Peb
Epiprobe muaj kev tsim kho vaj tse zoo: GMP chaw tsim khoom npog thaj tsam ntawm 2200 square metres, thiab tswj hwm ISO13485 kev tswj hwm zoo, uas ua tau raws li qhov yuav tsum tau ua ntawm txhua hom kev tshuaj ntsuam genetic reagent khoom;lub chaw kuaj mob kho mob npog thaj tsam ntawm 5400 square metres thiab muaj peev xwm ua tiav kev kuaj mob qog noj ntshav raws li lub chaw kuaj mob thib peb.Tsis tas li ntawd, peb muaj peb cov khoom tau txais ntawv pov thawj CE, suav nrog kev mob qog noj ntshav hauv tsev menyuam, mob qog noj ntshav endometrial thiab mob qog noj ntshav urothelial ntsig txog kev kuaj pom.
Epiprobe's cancer molecular detection thev naus laus zis tuaj yeem siv rau kev kuaj mob qog noj ntshav thaum ntxov, pabcuam kuaj mob, kuaj xyuas ua ntej thiab tom qab phais, kev tshuaj xyuas rov qab, uas khiav los ntawm tag nrho cov txheej txheem ntawm kev kuaj mob qog noj ntshav thiab kev kho mob, muab cov kev daws teeb meem zoo dua rau cov kws kho mob thiab cov neeg mob.
