TAGMe DNA Methylation Detection Kits (qPCR) rau Urothelial Cancer
KHOOM NTA
Precision
Validated ntau tshaj 3500 kuaj kuaj nyob rau hauv ob-dig muag multi-center kev tshawb fawb, cov khoom muaj ib tug tshwj xeeb ntawm 92.7% thiab rhiab heev ntawm 82.1%.
Yooj yim
Thawj Me-qPCR methylation nrhiav tshuab tuaj yeem ua tiav hauv ib kauj ruam hauv 3 teev yam tsis muaj kev hloov pauv bisulfite.
Tsis-invasive
Tsuas yog 30 mL ntawm cov zis yuav tsum tau kuaj xyuas 3 hom mob qog noj ntshav, suav nrog rau lub raum mob qog noj ntshav, mob qog nqaij hlav hauv plab, mob qog nqaij hlav zais zis tib lub sijhawm.
Daim ntawv thov scenarios
Auxiliary Diagnosis
Cov neeg raug kev txom nyem los ntawm qhov mob hematuria / xav tias muaj urothelial ( mob qog noj ntshav ureteral / raum mob qog noj ntshav)
Kev soj ntsuam kev pheej hmoo mob qog noj ntshav
Kev phais / kws khomob-xav tau cov pejxeem uas muaj urothelial carcinoma;
Kev soj ntsuam rov tshwm sim
Postoperative cov neeg uas muaj urothelial carcinoma
YUAV TSUM SIV
Cov khoom siv no yog siv rau hauv vitro qualitative nrhiav pom ntawm hypermethylation ntawm Urothelial Carcinoma (UC) noob nyob rau hauv urothelial specimens.Qhov txiaj ntsig zoo qhia tau tias muaj kev pheej hmoo siab ntawm UC, uas yuav tsum tau kuaj ntxiv cystoscope thiab / lossis histopathological kuaj.Ntawm qhov tsis sib xws, cov txiaj ntsig tsis zoo qhia tau tias qhov kev pheej hmoo ntawm UC tsawg, tab sis qhov kev pheej hmoo tsis tuaj yeem raug cais tawm tag nrho.Kev kuaj mob zaum kawg yuav tsum yog nyob ntawm cystoscope thiab / lossis cov txiaj ntsig histopathological.
DETECTION PRINCIPLE
Cov khoom siv no muaj cov nucleic acid extraction reagent thiab PCR nrhiav reagent.Nucleic acid yog muab rho tawm los ntawm magnetic-bead-based method.Cov khoom siv no yog ua raws li lub hauv paus ntsiab lus ntawm fluorescence quantitative PCR txoj kev, siv cov tshuaj methylation-specific real-time PCR cov tshuaj tiv thaiv los tshuaj xyuas cov qauv DNA, thiab ib txhij tshawb xyuas CpG qhov chaw ntawm UC noob thiab cov cim kev tswj xyuas zoo hauv cov khoom siv gene fragments G1 thiab G2.Qib methylation ntawm UC noob, hu ua Me tus nqi, yog xam raws li UC noob methylated DNA amplification Ct tus nqi thiab Ct tus nqi ntawm qhov siv.UC gene hypermethylation zoo lossis tsis zoo yog txiav txim siab raws li Me tus nqi.
DNA Methylation Detection Kits (qPCR) rau Urothelial Cancer
| Daim ntawv thov kev kho mob | Clinical auxiliary diagnosis ntawm urothelial cnacer;phais/chemotheray kev ntsuam xyuas kev ua tau zoo;postoperative recurrence xyuas |
| Kev kuaj gene | UC |
| Hom qauv | Urine exfoliated cell qauv ( zis sediment) |
| Kev sim | Fluorescence quantitative PCR technology |
| Cov qauv siv tau | AB 7500 |
| Packing specification | 48 xeem/kit |
| Kev cia khoom | Cov khoom siv A yuav tsum khaws cia ntawm 2-30 ℃ Cov khoom siv B yuav tsum khaws cia ntawm -20 ± 5 ℃ Siv tau mus txog 12 lub hlis. |
